Finding the right nattokinase supplement can feel tricky with so many brands claiming to offer the best product. You want something that actually works, comes from a trustworthy company, and fits your budget. That’s exactly why we put together this guide.
We tested and researched the top nattokinase brands on the market to help you skip the guesswork. Whether you’re looking for cardiovascular support or general wellness benefits, we’ve identified the brands that truly deliver quality and value. This review walks you through everything you need to know to choose confidently.
How We Selected the Best Nattokinase Brands
Our expert team spent weeks evaluating nattokinase supplements based on strict quality standards and real-world performance. We looked beyond marketing claims to examine what actually matters for your health and satisfaction.
We considered these key factors:
- Enzyme Activity (FU Count): We verified that each product contains therapeutic levels of fibrinolytic units for effectiveness
- Purity and Testing: We prioritized brands with third-party testing certificates and clean ingredient lists
- Manufacturing Standards: We checked for GMP-certified facilities and quality control processes
- Vitamin K2 Content: We noted whether products contain vitamin K2, which matters for those on blood thinners
- Customer Feedback: We analyzed thousands of verified reviews to gauge real-world results
- Value for Money: We compared dosage, quantity, and price to identify the best deals
- Company Reputation: We assessed brand history, transparency, and customer service quality
These criteria helped us separate genuinely effective supplements from overpriced or underdosed options.
10 Best Nattokinase Brands (Expert Review)
After careful evaluation, we’ve identified the nattokinase brands that consistently deliver quality, safety, and results.
1. Doctor’s Best
Doctor’s Best has earned its reputation through consistent quality and transparent labeling. Their nattokinase formula delivers 2,000 FUs per serving, which falls right in the therapeutic range most research supports. The company uses NSK-SD, a clinically studied form of nattokinase with vitamin K2 removed.
You’ll find their supplements in major retailers, which speaks to their established credibility. The capsules are easy to swallow and the dosing instructions are straightforward. Third-party testing and clean manufacturing practices set them apart from cheaper alternatives.
This brand suits people who want a reliable, well-researched option without paying premium prices. Their products consistently receive positive feedback from long-term users who appreciate the balance of quality and affordability.
2. NOW Foods
Their nattokinase product line includes options at different potency levels, giving you flexibility based on your needs. The brand has been around for over 50 years, building trust through consistent performance. NOW Foods manufactures in GMP-certified facilities and maintains rigorous quality standards that exceed industry requirements.
NOW Foods is perfect for budget-conscious consumers who refuse to compromise on quality. Their nattokinase contains 100mg per capsule with 2,000 FUs, matching what clinical studies typically use. The vegetarian capsules and minimal filler ingredients make this a clean choice.
They test for heavy metals, microbial contamination, and potency verification. You can access their extensive quality testing documentation on their website. Customer reviews frequently mention noticeable improvements in circulation and overall wellness.
3. Healthy Origins
Their transparent labeling tells you exactly what you’re getting in each capsule. Healthy Origins sources their nattokinase from trusted Japanese suppliers using traditional fermentation methods. This brand delivers exceptional value with their high-potency formula containing 2,000 FUs of nattokinase activity.
The company focuses specifically on cardiovascular health supplements, which means they’ve developed deep expertise in this area. Their manufacturing processes are closely monitored and they provide certificates of analysis upon request. The softgel format makes absorption efficient and convenient.
Healthy Origins works well for people who want a specialized brand focused on heart health rather than a general supplement company. Their customer service team is knowledgeable and responsive. The price point makes it accessible for long-term supplementation without breaking your budget.
4. Jarrow Formulas
Each capsule contains precise amounts that align with published research findings. They also provide detailed educational resources about how nattokinase works in your body. Jarrow Formulas uses NSK-SD nattokinase, which has extensive clinical research backing its safety and effectiveness.
This brand appeals to health-conscious consumers who want science-backed formulations from a company with strong research credentials. Jarrow’s quality control exceeds FDA requirements and they regularly update their formulations based on new findings. Their supplements are widely available both online and in health food stores.
The brand invests heavily in scientific research and collaborates with leading universities on supplement studies. Their formula is carefully crafted to support healthy blood flow and cardiovascular function. What distinguishes Jarrow is their focus on bioavailability and optimal dosing schedules.
5. Nutricost
The straightforward approach at Nutricost means you get pure nattokinase without unnecessary additives or inflated prices. Their supplements provide 2,000 FUs per serving in simple vegetarian capsules. The brand has built a loyal following by consistently delivering what they promise.
This brand suits practical buyers who want effective supplements without fancy packaging or marketing gimmicks. Customer reviews highlight the reliable results and excellent value. Nutricost’s nattokinase works particularly well for people maintaining long-term cardiovascular wellness routines.
Nutricost manufactures all products in FDA-registered, GMP-compliant facilities right here in the United States. Each batch undergoes testing for purity and potency before reaching consumers. Their transparent business practices and direct-to-consumer model keep costs reasonable.
6. Pure Encapsulations
Pure Encapsulations represents the premium end of the nattokinase market, targeting practitioners and patients seeking hypoallergenic formulations. Their products contain no artificial additives, GMOs, or common allergens. The company maintains pharmaceutical-grade quality standards throughout production.
This option is ideal for people with multiple allergies or those following strict dietary protocols. While the price is higher than many alternatives, you’re paying for exceptional purity and quality assurance. The brand’s reputation among functional medicine practitioners speaks to their commitment to therapeutic effectiveness.
Their nattokinase formula uses carefully selected enzymes with verified activity levels and purity profiles. Pure Encapsulations conducts extensive testing at multiple stages of manufacturing. Healthcare providers frequently recommend this brand to patients with sensitivities or specific dietary requirements.
7. Best Naturals
Best Naturals delivers solid performance at a competitive price point, making nattokinase accessible to more people. The brand focuses on providing straightforward supplements without unnecessary complexity. Their formula contains 2,000 FUs of enzyme activity per capsule with minimal fillers.
This brand works well for newcomers to nattokinase who want to try a quality product without a huge financial commitment. Customer feedback consistently mentions good results with circulation and general wellness. Best Naturals provides reliable customer support and stands behind their products with satisfaction guarantees.
What makes Best Naturals noteworthy is their commitment to USA-based manufacturing and quality testing protocols. They use vitamin K2-removed nattokinase, which is safer for people on certain medications. The capsules are easy to incorporate into daily routines.
8. Life Extension
Life Extension brings decades of research experience to their nattokinase formulation. This brand stands out through their comprehensive approach to cardiovascular health and commitment to evidence-based formulations. Their product contains standardized enzyme activity levels that remain stable throughout the shelf life.
Life Extension suits serious health enthusiasts who want supplements backed by substantial research and clinical data. The brand’s scientific advisory board includes leading researchers and physicians. While prices are higher, many users feel the quality justifies the investment for long-term wellness.
The company funds independent research on supplement efficacy and publishes findings in peer-reviewed journals. Life Extension uses premium ingredients and tests every batch for contaminants and potency. Their educational resources help you understand exactly how nattokinase supports your health goals.
9. Allergy Research Group
Each batch comes with a certificate of analysis verifying the nattokinase activity and confirming the absence of vitamin K2. The brand’s attention to detail sets them apart in the specialty supplement market. Allergy Research Group specializes in supplements for people with sensitivities and specific health concerns.
This option is perfect for individuals who’ve had reactions to other supplements or need guaranteed allergen-free products. Healthcare providers trust Allergy Research Group for patients with complex health situations. The price reflects the extra care taken in manufacturing, but for those who need it, the value is undeniable.
Their nattokinase formula is exceptionally pure and free from common allergens. The company works closely with healthcare practitioners to develop formulations that meet clinical needs. Their manufacturing process includes rigorous testing for purity, with special attention to removing potential allergens and contaminants.
10. Solaray
Solaray rounds out our list with a well-formulated nattokinase supplement that balances quality and accessibility. Their product delivers 2,000 FUs per serving using a clean, vegetarian formula. The brand has over 40 years of experience in the supplement industry and maintains strong quality standards.
Solaray works well for environmentally conscious consumers who want effective supplements from a socially responsible company. Their nattokinase has earned positive reviews for supporting cardiovascular wellness goals. The brand offers good value considering their quality standards and ethical business practices.
What makes Solaray appealing is their commitment to sustainable sourcing and environmentally responsible manufacturing practices. They verify ingredient quality from suppliers and conduct comprehensive testing throughout production. The company provides detailed product information and responsive customer service.
Final Thoughts
Choosing a nattokinase supplement comes down to matching your specific needs with the right brand. Whether you prioritize clinical research, allergen-free formulations, budget considerations, or premium quality, there’s an excellent option on this list for you.
The brands we’ve featured all meet high standards for purity, potency, and manufacturing quality. Consider your health goals, any dietary restrictions, and your budget as you make your selection. Each of these companies has earned its place through consistent performance and customer satisfaction.